Apidra package insert pdf

Apidra insulin glulisine injection, for subcutaneous or. If apidra is mixed with nph insulin, draw apidra into the syringe first and inject immediately after. Highlights of prescribing information hyperglycemia or. Prescription lantus is a longacting insulin used to treat adults with type 2 diabetes and adults and pediatric patients children 6 years and older with type 1 diabetes for the control of high blood sugar. In order to monitor the safety of astrazeneca products, we encourage reporting any side effects experienced while taking an astrazeneca product to the az information center at 18002369933. Moderate patients with diabetes mellitus should be monitored apidra package insert during somatropin recombinant rhgh jnsert. Do not mix apidra for subcutaneous injection with insulin preparations other than nph insulin.

Important notice for users you are about to access astrazeneca historic archive material. Apidra insulin glulisine injection, for subcutaneous or intravenous use. The apidra solostar prefilled pen dials in 1unit increments. Moderate monitor blood glucose levels regularly in patients with diabetes, apidra package insert when lanreotide treatment is initiated or when the dose is altered. Highlights of prescribing information these highlights.

Highlights of prescribing information these highlights do not include all the information needed to use enbrel safely and effectively. Mar 17, 2020 apidra solostar unitsml solution for injection in a prefilled pen. If a foil package, blister card or strip is not refrigerated, the contents must be used within 10 days. Videos demonstrating insertion and removal are available online for trained healthcare providers. Highlights of prescribing information these highlights do. Do not use apidra if you have low blood sugar reaction or if you are allergic to insulin glulisine or any of the ingredients in apidra. The mean baselinecorrected serum calcium for the aredia 60mg and etidronate disodium groups were.

When used in an external insulin pump for subcutaneous infusion, apidra should not be mixed. Apidra is a recombinant insulin analog that is equipotent to human insulin i. Long acting insulin toujeo insulin glargine injection. Humulinn isophane insulinhumansuspension, for subcutaneous use initial u. Pharmacist and physician resources and faqs toujeo. Apidra dosing apidra insulin glulisine injection 100 unitsml. Lantus can be refrigerated until the expiration date.

Solostar, the instructions for use included in the package leaflet must be read carefully. The united kingdom prospective diabetes study demonstrated the progressive decline in. Do not store the pen with the needle attached to prevent leaking, blocking the needle, and air. Inject subcutaneously into the thigh, upper arm, or abdomen 2. The safety and efficacy of afrezza in patients who smoke has not been established.

Rotate injection sites to reduce risk of lipodystrophy and localized cutaneous amyloidosis 2. Apidra package insert pdf apidra solostar unitsml solution for injection in a prefilled pen patient the patient information leaflet pil is. Has the participant had an adverse reaction to or would be reasonably expected to have an adverse reaction to a majority two or more in a class with at least two alternatives or one in a. Hyperglycemia or hypoglycemia with changes in insulin regimen. Millions of people every day count on lantus to help them manage their a1c and control their blood sugar. Nov 15, 2019 provides trustworthy package insert and label information about marketed drugs as submitted by manufacturers to the us food and drug administration.

Dailymed apidra insulin glulisine injection, solution. Dont drink alcohol or use other medicines that contain alcohol. Rotateinfusion sites within the same region to reduce the risk of. Guide for storage of insulin wisconsin department of. All studies in the edition clinical program were 26week, openlabel, controlled, titratetotarget, noninferiority. Apidra package insert pdf apidra solostar unitsml solution for injection in a prefilled pen patient the patient information leaflet pil is the leaflet included in the pack chris may field menu. Apidra is approved to be taken within 15 minutes before or within 20 minutes after starting a meal. Highlights of prescribing information these highlights do not include all the information needed to use toujeo safely and effectively. After 15 days of use, the inhaler must be discarded and replaced with a new inhaler.

More severe episodes with coma, seizure, or neurologic impairment may be treated with intramuscular subcutaneous glucagon or. See full prescribing information for important administration instructions 2. Alternatively, you can report any side effects of prescription drugs directly to the fda. Administer humalog u100 by continuous subcutaneous infusion in a region recommended in the instructions from the pump manufacturer. Nov 15, 2019 never share needles or syringes with another person. Aspart novolog 5 15 min 30 90 min lispro humalog, admelog apidra short acting regular 30 60 min 2 3 hrs 5 8 hrs basal intermediate nph 2 4 hrs 4 10 hrs 10 16 hrs long acting detemir levemir 3 8 hrs no peak 6 24 hrs glargine lantus basaglar 2 4 hrs 20 24 hrs. What information is on the taxol paclitaxel package insert. Thirty patients were randomized to receive aredia and 35 to receive etidronate disodium. Apidra is indicated to improve glycemic control in adults and children with diabetes mellitus. Lantus insulin glargine 100 unitsml is the most prescribed long acting insulin. Apidra is stable at room temperature for 48 hours only in normal saline solution 0. The most common side effect of any insulin, including toujeo, is low blood sugar hypoglycemia, which may be serious and lifethreatening.

Early introduction of insulin therapy can attain and maintain glucose targets when oral antidiabetic drug oad regimens have failed to achieve glycemic goals, thereby reducing the risk. Highlights of prescribing information these highlights do not include all the information needed to use humulinnsafely and effectively. Apidra package insert pdf apidra solostar unitsml solution for injection in a prefilled pen patient the patient information leaflet pil is the leaflet included in the pack with a. Before using a different insulin with the omnipod system, check the insulin drug label to make sure it can be used with a pump. It has a dark blue injection buttonwith a raised ring on the top.

Apidra given 2 minutes apidra pre before the start of a meal compared to regular human insulin given 30 minutes regular 30 min before start of the meal see figure 1a and compared to regular human insulin regular pre given 2 minutes before a meal see figure 1b. The safety of novolog was evaluated in two treattotarget trials of 6 months duration, conducted in subjects with type 1 diabetes or type 2 diabetes see clinical studies 14. If apidra is mixed with nph insulin, draw apidra into the syringe first and inject immediately after mixing. Adjustments in drug dosage, meal patterns, or exercise may be needed. Apidra insulin glulisine injection rdna origin is a recombinant human insulin analogue indicated for. Important safety information for apidra insulin glulisine injection 100 unitsml. Limitations of use 5not recommended for the treatment of diabetic ketoacidosis. Apidra insulin glulisine injection rdna origin is a recombinant. Do not use this solostarif the insulin is cloudy, colored or has particles.

Unscrew the capped needle and throw it away see disposing of pens and needlessection below. The use of afrezza is not recommended in patients who smoke or who have recently stopped smoking. How to use apidra solostar pen apidra insulin glulisine. Information for the user apidra solostar 100 unitsml solution for injection in a prefilled pen insulin glulisine talk to your doctor, pharmacist or nurse before using apidra. Your health professional has decided that solostar is appropriate for you, based on your ability to handle solostar. Apidra insulin glulisine injection, solution apidra. Apidra solostar unitsml solution for injection in a prefilled pen. With apidra mealtime insulin, you can help manage your blood sugar at mealtime. Novolog, humalog, and apidra are compatible with the omnipod system for use up to 72 hours 3 days. Dailymed humulin r insulin human injection, solution. Click here for full prescribing information for apidra. Enbrel etanerceptinjection, for subcutaneous use enbrel etanercept for injection, for subcutaneous use initial u.

This information is not intended to be used as a tool to prescribe medication or provide other clinical services. How to use your lantus solostar pen what is lantus. Jakafi is indicated for treatment of intermediate or highrisk myelofibrosis mf, including primary mf, postpolycythemia vera mf and postessential thrombocythemia mf in adults. The data in table 1 reflect the exposure of 596 patients with type 1 diabetes to novolog in one clinical trial with a mean exposure duration to novolog of 24. Aug 10, 2019 apidra solostar unitsml solution for injection in a prefilled pen. Afrezza in patients with chronic lung disease has not been established.

Apidra may be infused subcutaneously by external insulin infusion pumps. Any reference in these archives to astrazeneca products or their uses may not reflect current medical knowledge and should not be used as a source of information on the present product label, efficacy data or safety data. Apidra package insert pdf in turn, under these presuppositions the contractor does not assume liability that, for disturbances specified vorlagd bids that without disturbances would have led to a conclusion of contract, can only be submitted incomplete or with delay. Glucose monitoring is essential for patients receiving insulin therapy. Always use a new sterile needle for each injection. Administer only under medical supervision after diluting to concentrations from 0. The afrezza inhaler can be used for up to 15 days from the date of. Moderate green tea catechins have been apidra package insert to decrease serum glucose concentrations.

Guide for storage of insulin every effort is made to assure the accuracy of the attached information. Humulin r is produced by recombinant dna technology utilizing a nonpathogenic laboratory strain of escherichia coli. Dec 06, 2019 never share an apidra solostar pen between patients, even if the needle is changed. Changes in insulin strength, manufacturer, type, or method of administration may affect glycemic control and. Follow closely the instructions for dose, monitoring blood tests, diet and physical activity physical work and exercise as discussed with your. Patient and family education regarding hypoglycemia management is apidra package insert the patient and patients family should be instructed on how to recognize packsge manage the symptoms of hypoglycemia. Apidra insulin glulisine rdna origin injection solution for injection.

Apidra is not compatible with dextrose solution and ringers solution. Toujeo has been studied versus lantus insulin glargine injection 100 unitsml in four pivotal clinical trials the edition study program involving more than 3000 patients and in two euglycemic clamp studies to assess pharmacokinetics pk and pharmacodynamics pd. Aspart novolog 5 15 min 30 90 min lispro humalog admelog apidra short acting regular 30 60 min 2 3 hrs 5 8 hrs basal intermediate nph 2 4 hrs 4 10 hrs 10 16 hrs long acting detemir levemir 3 8 hrs no peak 6 24 hrs glargine lantus basaglar 2. Apidra solostar 100 unitsml solution for injection in a prefilled pen. Apidra, inninsulin glulisine european medicines agency. Highlights of prescribing information these highlights do not include all the information needed to use humalog safely and effectively. Call the merck national service center at 18778884231 if you have any questions. Apidra should be given by subcutaneous injection shortly 015 min before or soon after meals or by. This information is intended as a tool for oqa surveyors to assist in evaluating medication therapy only. While using toujeo, do not drive or operate heavy machinery until you know how toujeo affects you. Humulin r insulin human injection is a shortacting human insulin for subcutaneous or intravenous use. Highlights of prescribing information thiazolidinediones. Mild episodes of hypoglycemia usually can be treated with oral glucose.

Novolog is available in the following package sizes. If you are unsure of the necessary steps to safely insert andor remove nexplanon, do not attempt the procedure. Highlights of prescribing information administration. Humulin r u500 prescribing informationlinr5000005uspi. Inject the dose by pressing the pushbutton all the way in until the 0 lines up with the pointer see diagram i. Every individual package label entry contains a unique identifier which can. Highlights of prescribing information these highlights do not. Aug 31, 2018 moderate green tea catechins have been apidra package insert to decrease serum glucose concentrations. Apidra insulin glulisine injection rdna origin is a recombinant human insulin. Deplin tablets folic acid, when administered in daily doses above 800 mcg, may increase the amount of unmetabolized folic description less likely than folic acid to accelerate the growth of existing neoplasms. Before using solostar, the instructions for use included in the package leaflet must be read carefully. Apidra, humulin excluding u 500, humalog medical necessity prior authorization form confidential page 2 of 2 revised. Fda approves admelog, the first shortacting followon insulin product to treat diabetes.